WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:defense response       ID:GO:0006952
C=1107; O=20; E=3.86; R=5.18; rawP=2.57e-10; adjP=1.22e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000128383 NA APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 200315 ENSG00000128383
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
5  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
6  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
7  ENSG00000170866 NA LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 11026 ENSG00000170866
8  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
9  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
10  ENSG00000103313 NA MEFV Mediterranean fever 4210 ENSG00000103313
11  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
12  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116
13  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
14  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
15  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
16  ENSG00000166527 NA CLEC4D C-type lectin domain family 4, member D 338339 ENSG00000166527
17  ENSG00000163421 NA PROK2 prokineticin 2 60675 ENSG00000163421
18  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
19  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
20  ENSG00000171049 NA FPR2 formyl peptide receptor 2 2358 ENSG00000171049


Database:biological process       Name:defense response to fungus       ID:GO:0050832
C=20; O=5; E=0.07; R=71.72; rawP=6.27e-09; adjP=1.49e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
3  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
4  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
5  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221


Database:biological process       Name:immune response       ID:GO:0006955
C=1071; O=17; E=3.73; R=4.55; rawP=5.98e-08; adjP=9.47e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000128383 NA APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 200315 ENSG00000128383
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
5  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
6  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
7  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
8  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
9  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
10  ENSG00000103313 NA MEFV Mediterranean fever 4210 ENSG00000103313
11  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
12  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116
13  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
14  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
15  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
16  ENSG00000166527 NA CLEC4D C-type lectin domain family 4, member D 338339 ENSG00000166527
17  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:biological process       Name:response to fungus       ID:GO:0009620
C=34; O=5; E=0.12; R=42.19; rawP=1.09e-07; adjP=1.29e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
3  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
4  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
5  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221


Database:biological process       Name:immune system process       ID:GO:0002376
C=1792; O=21; E=6.25; R=3.36; rawP=1.85e-07; adjP=1.76e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000100985 NA MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 ENSG00000100985
3  ENSG00000128383 NA APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 200315 ENSG00000128383
4  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
5  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
6  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
7  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
8  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
9  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
10  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
11  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
12  ENSG00000103313 NA MEFV Mediterranean fever 4210 ENSG00000103313
13  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
14  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116
15  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
16  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
17  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
18  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
19  ENSG00000166527 NA CLEC4D C-type lectin domain family 4, member D 338339 ENSG00000166527
20  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
21  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464


Database:biological process       Name:innate immune response       ID:GO:0045087
C=539; O=12; E=1.88; R=6.39; rawP=2.36e-07; adjP=1.87e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000128383 NA APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 200315 ENSG00000128383
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
5  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
6  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
7  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
8  ENSG00000166527 NA CLEC4D C-type lectin domain family 4, member D 338339 ENSG00000166527
9  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
10  ENSG00000103313 NA MEFV Mediterranean fever 4210 ENSG00000103313
11  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
12  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116


Database:biological process       Name:response to bacterium       ID:GO:0009617
C=349; O=10; E=1.22; R=8.22; rawP=2.81e-07; adjP=1.91e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000100985 NA MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 ENSG00000100985
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
5  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
6  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
7  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
8  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
9  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
10  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221


Database:biological process       Name:defense response to bacterium       ID:GO:0042742
C=142; O=7; E=0.50; R=14.14; rawP=5.67e-07; adjP=3.37e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
3  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
4  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
5  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
6  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
7  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438


Database:biological process       Name:neutrophil chemotaxis       ID:GO:0030593
C=50; O=5; E=0.17; R=28.69; rawP=7.92e-07; adjP=4.18e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
3  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
4  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
5  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535


Database:biological process       Name:disruption of cells of other organism       ID:GO:0044364
C=23; O=4; E=0.08; R=49.89; rawP=1.10e-06; adjP=4.35e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
3  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
4  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221


Database:molecular function       Name:RAGE receptor binding       ID:GO:0050786
C=9; O=3; E=0.03; R=106.14; rawP=2.41e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
3  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221


Database:molecular function       Name:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds       ID:GO:0016810
C=114; O=6; E=0.36; R=16.76; rawP=1.43e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112303 NA VNN2 vanin 2 8875 ENSG00000112303
2  ENSG00000128383 NA APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 200315 ENSG00000128383
3  ENSG00000159339 NA PADI4 peptidyl arginine deiminase, type IV 23569 ENSG00000159339
4  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
5  ENSG00000117115 NA PADI2 peptidyl arginine deiminase, type II 11240 ENSG00000117115
6  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438


Database:molecular function       Name:interleukin-8 receptor activity       ID:GO:0004918
C=2; O=2; E=0.01; R=318.42; rawP=9.66e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871


Database:molecular function       Name:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines       ID:GO:0016813
C=12; O=3; E=0.04; R=79.60; rawP=6.27e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000159339 NA PADI4 peptidyl arginine deiminase, type IV 23569 ENSG00000159339
2  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
3  ENSG00000117115 NA PADI2 peptidyl arginine deiminase, type II 11240 ENSG00000117115


Database:molecular function       Name:C-X-C chemokine binding       ID:GO:0019958
C=3; O=2; E=0.01; R=212.28; rawP=2.89e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871


Database:molecular function       Name:Toll-like receptor 4 binding       ID:GO:0035662
C=3; O=2; E=0.01; R=212.28; rawP=2.89e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:molecular function       Name:interleukin-8 binding       ID:GO:0019959
C=3; O=2; E=0.01; R=212.28; rawP=2.89e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871


Database:molecular function       Name:Toll-like receptor binding       ID:GO:0035325
C=4; O=2; E=0.01; R=159.21; rawP=5.77e-05; adjP=0.0007
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:molecular function       Name:arachidonic acid binding       ID:GO:0050544
C=5; O=2; E=0.02; R=127.37; rawP=9.60e-05; adjP=0.0008
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:molecular function       Name:icosatetraenoic acid binding       ID:GO:0050543
C=6; O=2; E=0.02; R=106.14; rawP=0.0001; adjP=0.0008
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
2  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:cellular component       Name:extracellular region       ID:GO:0005576
C=2140; O=20; E=6.78; R=2.95; rawP=3.91e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000100985 NA MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 ENSG00000100985
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000008438 NA PGLYRP1 peptidoglycan recognition protein 1 8993 ENSG00000008438
5  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
6  ENSG00000170866 NA LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 11026 ENSG00000170866
7  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
8  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
9  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
10  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
11  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
12  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116
13  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
14  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
15  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
16  ENSG00000118113 NA MMP8 matrix metallopeptidase 8 (neutrophil collagenase) 4317 ENSG00000118113
17  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
18  ENSG00000163421 NA PROK2 prokineticin 2 60675 ENSG00000163421
19  ENSG00000021355 NA SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1992 ENSG00000021355
20  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220


Database:cellular component       Name:extracellular space       ID:GO:0005615
C=856; O=9; E=2.71; R=3.32; rawP=0.0013; adjP=0.0225
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000100985 NA MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 ENSG00000100985
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000118113 NA MMP8 matrix metallopeptidase 8 (neutrophil collagenase) 4317 ENSG00000118113
5  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
6  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
7  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
8  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
9  ENSG00000021355 NA SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1992 ENSG00000021355


Database:cellular component       Name:anchored to membrane       ID:GO:0031225
C=144; O=4; E=0.46; R=8.77; rawP=0.0011; adjP=0.0225
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
2  ENSG00000112303 NA VNN2 vanin 2 8875 ENSG00000112303
3  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
4  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747


Database:cellular component       Name:extracellular region part       ID:GO:0044421
C=1099; O=10; E=3.48; R=2.87; rawP=0.0021; adjP=0.0273
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000100985 NA MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 4318 ENSG00000100985
3  ENSG00000148346 NA LCN2 lipocalin 2 3934 ENSG00000148346
4  ENSG00000118113 NA MMP8 matrix metallopeptidase 8 (neutrophil collagenase) 4317 ENSG00000118113
5  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
6  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
7  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839
8  ENSG00000118520 NA ARG1 arginase, liver 383 ENSG00000118520
9  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
10  ENSG00000021355 NA SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1992 ENSG00000021355


Database:cellular component       Name:cell periphery       ID:GO:0071944
C=4377; O=23; E=13.86; R=1.66; rawP=0.0049; adjP=0.0510
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112303 NA VNN2 vanin 2 8875 ENSG00000112303
2  ENSG00000126262 NA FFAR2 free fatty acid receptor 2 2867 ENSG00000126262
3  ENSG00000171051 NA FPR1 formyl peptide receptor 1 2357 ENSG00000171051
4  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
5  ENSG00000157551 NA KCNJ15 potassium inwardly-rectifying channel, subfamily J, member 15 3772 ENSG00000157551
6  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
7  ENSG00000182885 NA GPR97 G protein-coupled receptor 97 222487 ENSG00000182885
8  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
9  ENSG00000170866 NA LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 11026 ENSG00000170866
10  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
11  ENSG00000164047 NA CAMP cathelicidin antimicrobial peptide 820 ENSG00000164047
12  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
13  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
14  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
15  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
16  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
17  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
18  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
19  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
20  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
21  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
22  ENSG00000254415 NA SIGLEC14 sialic acid binding Ig-like lectin 14 100049587 ENSG00000254415
23  ENSG00000171049 NA FPR2 formyl peptide receptor 2 2358 ENSG00000171049


Database:cellular component       Name:plasma membrane       ID:GO:0005886
C=4289; O=22; E=13.58; R=1.62; rawP=0.0085; adjP=0.0737
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112303 NA VNN2 vanin 2 8875 ENSG00000112303
2  ENSG00000126262 NA FFAR2 free fatty acid receptor 2 2867 ENSG00000126262
3  ENSG00000171051 NA FPR1 formyl peptide receptor 1 2357 ENSG00000171051
4  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
5  ENSG00000157551 NA KCNJ15 potassium inwardly-rectifying channel, subfamily J, member 15 3772 ENSG00000157551
6  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
7  ENSG00000182885 NA GPR97 G protein-coupled receptor 97 222487 ENSG00000182885
8  ENSG00000143546 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
9  ENSG00000170866 NA LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 11026 ENSG00000170866
10  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
11  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
12  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
13  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
14  ENSG00000163221 NA S100A12 S100 calcium binding protein A12 6283 ENSG00000163221
15  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
16  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
17  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
18  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
19  ENSG00000163220 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
20  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
21  ENSG00000254415 NA SIGLEC14 sialic acid binding Ig-like lectin 14 100049587 ENSG00000254415
22  ENSG00000171049 NA FPR2 formyl peptide receptor 2 2358 ENSG00000171049


Database:cellular component       Name:integral to plasma membrane       ID:GO:0005887
C=1220; O=9; E=3.86; R=2.33; rawP=0.0137; adjP=0.1018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126262 NA FFAR2 free fatty acid receptor 2 2867 ENSG00000126262
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
3  ENSG00000157551 NA KCNJ15 potassium inwardly-rectifying channel, subfamily J, member 15 3772 ENSG00000157551
4  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
5  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
6  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
7  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
8  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
9  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=9; E=4.00; R=2.25; rawP=0.0169; adjP=0.1075
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000126262 NA FFAR2 free fatty acid receptor 2 2867 ENSG00000126262
2  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
3  ENSG00000157551 NA KCNJ15 potassium inwardly-rectifying channel, subfamily J, member 15 3772 ENSG00000157551
4  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
5  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
6  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
7  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
8  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
9  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535


Database:cellular component       Name:intrinsic to membrane       ID:GO:0031224
C=5437; O=25; E=17.22; R=1.45; rawP=0.0186; adjP=0.1075
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112303 NA VNN2 vanin 2 8875 ENSG00000112303
2  ENSG00000170956 NA CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 1084 ENSG00000170956
3  ENSG00000126262 NA FFAR2 free fatty acid receptor 2 2867 ENSG00000126262
4  ENSG00000171051 NA FPR1 formyl peptide receptor 1 2357 ENSG00000171051
5  ENSG00000180871 NA CXCR2 chemokine (C-X-C motif) receptor 2 3579 ENSG00000180871
6  ENSG00000157551 NA KCNJ15 potassium inwardly-rectifying channel, subfamily J, member 15 3772 ENSG00000157551
7  ENSG00000188404 NA SELL selectin L 6402 ENSG00000188404
8  ENSG00000182885 NA GPR97 G protein-coupled receptor 97 222487 ENSG00000182885
9  ENSG00000101307 NA SIRPB1 signal-regulatory protein beta 1 10326 ENSG00000101307
10  ENSG00000173535 NA TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8794 ENSG00000173535
11  ENSG00000103569 NA AQP9 aquaporin 9 366 ENSG00000103569
12  ENSG00000162747 NA FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2215 ENSG00000162747
13  ENSG00000186529 NA CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 4051 ENSG00000186529
14  ENSG00000187116 NA LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 353514 ENSG00000187116
15  ENSG00000119535 NA CSF3R colony stimulating factor 3 receptor (granulocyte) 1441 ENSG00000119535
16  ENSG00000186431 NA FCAR Fc fragment of IgA, receptor for 2204 ENSG00000186431
17  ENSG00000183019 NA C19orf59 chromosome 19 open reading frame 59 199675 ENSG00000183019
18  ENSG00000124731 NA TREM1 triggering receptor expressed on myeloid cells 1 54210 ENSG00000124731
19  ENSG00000115607 NA IL18RAP interleukin 18 receptor accessory protein 8807 ENSG00000115607
20  ENSG00000008516 NA MMP25 matrix metallopeptidase 25 64386 ENSG00000008516
21  ENSG00000166527 NA CLEC4D C-type lectin domain family 4, member D 338339 ENSG00000166527
22  ENSG00000198960 NA ARMCX6 armadillo repeat containing, X-linked 6 54470 ENSG00000198960
23  ENSG00000163464 NA CXCR1 chemokine (C-X-C motif) receptor 1 3577 ENSG00000163464
24  ENSG00000254415 NA SIGLEC14 sialic acid binding Ig-like lectin 14 100049587 ENSG00000254415
25  ENSG00000171049 NA FPR2 formyl peptide receptor 2 2358 ENSG00000171049


Database:cellular component       Name:Golgi lumen       ID:GO:0005796
C=77; O=2; E=0.24; R=8.20; rawP=0.0248; adjP=0.1290
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164821 NA DEFA4 defensin, alpha 4, corticostatin 1669 ENSG00000164821
2  ENSG00000239839 NA DEFA3 defensin, alpha 3, neutrophil-specific 1668 ENSG00000239839




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).